Targeted Protein Degradation (TPD) involves the use of heterobifunctional small molecule "degraders" (e.g. Featured Product Range: PROTAC ® Degraders & Targeted Protein Degradation Read more about the technique and tools available in our Chemogenetics Research Bulletin.
These tools allow for interrogation of neuronal activity in vivo.
One of the latest editions to the catalog is our chemogenetic range, which includes highly potent DREADD ligands and PSEMs. We always strive to be the first to market, making the latest research tools commercially available. Our portfolio includes high purity GPCR agonists, antagonists, PAMs, NAMs and biased agonists, as well as enzyme inhibitors, ion channel modulators and fluorescent probes and dyes. Tocris Bioscience has been supporting scientists since 1982! Our catalog comprises over 4500 gold standard and cutting-edge tools, covering many research areas including cancer, cardiovascular, endocrinology, immunology, pain and inflammation, respiratory system, stem cells and cell and gene therapy. The answer of 19.713 mg appears in the Mass box.Enter 10 into the Volume box and select the correct unit (milliliter).Enter 10 into the Concentration box and select the correct unit (millimolar).Enter 197.13 into the Molecular Weight (MW) box.What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol? Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol) An example of a molarity calculation using the Tocris molarity calculator The Tocris molarity calculator is based on the following equation: *When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).
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